As stated by reports, the explosion tool place at 6:30 am (0430 GMT) on Saturday, also shook the nearby supreme court in central Cairo.
An explosion has hit the Italian consulate in the Egyptian city of Cairo.
Medics at the site of the blast said it wounded two policemen stationed outside the consulate and three passers-by.
State news agency MENA cited a witness as saying the explosion has caused massive destruction to the building. Islamist militants seeking to topple the government have claimed responsibility for recent roadside bombs and suicide bombing attacks.
The consulate was closed at the time.