At least 150 people were injured after two trains collided close to the Booysens train station in Johannesburg, paramedics told the BBC.
Ms Mofokeng said authorities were still gathering information about the collision. In late April, two trains collided at a station east of Johannesburg, killing one and injuring more than 200 others.
No fatalities had been reported by late last night.
The injuries sustained by passengers range from minor to serious, according to ER24.
Firefighters searched for commuters who may have been trapped inside the train cars.
Meiring could not yet rule out the possibility of loss of life. “We are hoping for the best, but we are expecting the worst”.
Radebe earlier said those injured numbered more than 400.
The cause of the accident is officially unknown. Both are believed to have been Soweto-bound commuter trains.
“239 people were injured, we think none of them were critically injured”, Metrorail spokeswoman Lillian Mofokeng told African News Agency.
The commuter said people were crying and praying. “No fatalities or critical injuries reported yet”. Some reports claim the train crash was a result of a moving train running into a stationary one.
The crash between the two commuter trains left over 300 people injured.