It was 2-0 soon four minutes later when Aguero had an easy tap-in after Heurelho Gomes made a mess of a cross from David Silva.
Summer recruit Mohamed Salah’s tying goal secured a point for the Reds but even he can’t match the brilliance of Mane, who is serving a three-match suspension after being sent off against Manchester City last weekend.
City were in exuberant mood and added a third before the break when the excellent Gabriel Jesus latched on to Aguero’s cute pass to stroke home in the 38th minute.
City leads the Premier League in scoring with 16 goals through five matches.
Defender John Stones grabbed the headlines with two goals at De Kuip while Aguero and Jesus also got on the scoresheet.
Meanwhile, Raheem Sterling is available after serving his one-match ban last week, and is in contention to make the starting lineup with Guardiola likely to shuffle his pack to keep all his charges fit and firing. This season, they seem to have that system down pat.
Toure then became an important figure for the remainder of the campaign when Guardiola restored him to the first-team squad in November. The big clubs win the games and that is the big difference to the big teams. Below is a ratings form for you to fill out with how you rate each Manchester City player’s performance.
Three clean sheets on the spin have seen the Hornets play with a grit which was starkly absent from their game last term, in spite of a ever-rotating cast in defence.
Jurgen Klopp’s Liverpool endured more frustration as they were held to a 1-1 draw by battling Burnley at Anfield.
Four minutes later, Jesus skipped down the left flank before feeding the ball to David Silva inside the box and the Spaniard squared it across the face of goal where Aguero arrived unchallenged to poke the ball home.
Liverpool responded in kind three minutes later.
The last victory, however, came back in March 1989 when Iwan Roberts scored the only goal of the game in the second division.
“Watford are just two points behind us”.
Newcastle finds itself near the top of the table early in its first season back in the Premier League.
Talks of a hangover from a midweek trip to Feyenoord in the Champions League were quickly put to bed when Manchester City got started at Vicarage Road.