Closed-loop insulin delivery system can improve glucose control and reduce

Previous studies have reported both favourable and adverse impacts of high-protein diet in type 2 diabetes. Kowalski said. Computer modelling was used to calculate the link between HbA1c and dementia, which also adjusted for variables including age, sex, duration of diabetes, marital status, income, education, smoking status, systolic blood pressure, body mass index, estimated kidney function, statins, levels of urine in protein, type of diabetes medication, atrial fibrillation, stroke and blood pressure medications.

Diabetes may be harder on women’s hearts than it is on men’s, according to research presented Monday at the annual meeting of the European Association for the Study of Diabetes in Stockholm, Sweden. “Further studies are needed to replicate these results and to evaluate potential biological mechanisms underlying the observed associations”, the study authors said in a news release. “We’ve now put people in the real world for a decently-long period of time and compared them to the best in class standard of care, and it’s out-performed it. It fact, it outperformed it quite well”.

The precision and accuracy was in favor of the machine, where among the 33 participants, 68% of them maintained their blood glucose with the help of the system at 70 to 170 mg/dL against 57% when they do pump it on their own.

According to the researchers, the improvements were more effective at night due to levels stayed in the normal range 59 percent of the time versus 29 percent without using the software. The adult study participants lived in the United Kingdom , Germany and Austria. With the children, blood glucose levels stayed within target ranges 60 percent of the time with the closed-loop system but only 34 percent of the time when increased insulin injections were not automatic.

The benefits of tighter nighttime control seemed to carry over to the day as well, said the research team, led by Dr. Hood Thabit of the University of Cambridge.

Researchers found that the results weren’t all good news for the closed-loop systems as one adult suffered severe hypoglycemia when the system lost connectivity because the battery ran out.

The research discuss the discovery that extended use of a closed-loop system over a period of 12 weeks in a personal home setting, during free daily living and without the requisite for close supervision is acceptable in adults, children, and even adolescents with type 1 diabetes.

“Systems with threshold-suspend control and predictive low-glucose suspend control may reduce the risk of hypoglycemia, but the systems are not created to step up insulin delivery and do not address the issue of hyperglycemia”, the authors wrote.

Within a couple of years, there has been a race to develop and test closed-loop insulin systems, which are often referred to as artificial pancreases or artificial beta cells.