More Fat Means More Difficult Weight Loss
He added that excess stored fat in the body is fighting against efforts to lose weight by burning it off at the molecular level.
What’s more, they found that the more fat cells a person has, the more amount of sLR11 protein gets produced in that person’s body.
In their paper the authors suggest that sLR11 helps fat cells resist burning too much fat during “spikes” in other metabolic signals following large meals or short term drops in temperature. This most recent research also supports this consensus, in the sense that scientists have found that certain weight loss procedures worked for some individuals but did not help others. The researchers have especially pointed out two main benefits of the findings- Firstly, by knowing about the protein and its working with regard to fat cells can encourage development of new ways to burn more fat making weight loss process a smooth one.
Blame it on a protein released by the body that works against the depletion of fat cells; more fat on the body means more of the protein that “actively inhibits weight loss.”
The presence of this protein’s amount is dependent on the amount of fat in the body. The findings shed light in future treatments for obesity and obesity-induced diseases like metabolic syndrome. Thus, the count of this protein circulating in the blood correlated with total fat mass.
The more fat cells a person has, the more that person’s body will resist weight loss, the researchers said.
Further examinations revealed that in these mice, genes normally associated with brown adipose tissue were more active in white adipose tissue (which normally stores fat for energy release). Its levels increase in connection to the fat mass, which makes it harder for fat people to lose weight.
This comes as a confirmation for millions of fat people all over the world who until know haven’t had any idea why it is so hard for them to lose weight, despite their tremendous efforts.
Study on mice showed that those mice that lack LR1 protein are protected from diet-inducing obesity.
“We have found an important mechanism that could be targeted not just to help increase people’s ability to burn fat, but also help people with conditions where saving energy is important such as anorexia nervosa”, lead researcher Toni Vidal-Puig said.